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Actual lens positions of three intraocular lenses in highly myopic eyes: an ultrasound biomicroscopy-based study
  1. Jiao Qi1,2,3,4,
  2. Wenwen He1,2,3,4,
  3. Keke Zhang1,2,3,4,
  4. Donglin Guo1,2,3,4,
  5. Yu Du1,2,3,4,
  6. Yi Lu1,2,3,4,
  7. Xiangjia Zhu1,2,3,4
  1. 1Department of Ophthalmology, Fudan University Eye Ear Nose and Throat Hospital, Shanghai, China
  2. 2NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, People's Republic of China
  3. 3Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, People's Republic of China
  4. 4State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, People's Republic of China
  1. Correspondence to Dr Xiangjia Zhu, Department of Ophthalmology, Fudan University Eye Ear Nose and Throat Hospital, Shanghai, Shanghai, China; zhuxiangjia1982{at}126.com

Abstract

Aim To evaluate the actual lens positions (ALPs) of three intraocular lenses (IOLs) in highly myopic eyes and to identify relevant factors using ultrasound biomicroscopy (UBM).

Methods Ninety-three highly myopic eyes (93 patients) that underwent uneventful cataract surgery were included: 36 eyes were implanted with Zeiss 409MP IOLs, 27 with Rayner 920H IOLs and 30 with HumanOptics MCX11 IOLs. The prediction error (PE), ALP determined by UBM and the factors associated with ALP at 3 months after surgery were evaluated.

Results The eyes in the MCX11 IOL group had a more hyperopic PE (0.67±0.45 diopters (D)) and greater ALP (4.86±0.39 mm) than those in the 409MP and 920H IOL groups at 3 months after surgery (PE: −0.25±0.54 and −0.16±0.65 D, respectively; ALP: 4.34±0.26 and 4.14±0.32 mm, respectively). The MCX11 IOLs showed more backward bending deformation after surgery than 409MP and 920H IOLs. The radius of curvature of the IOL was negatively correlated with ALP (r=−0.532, p=0.002) in the MCX11 IOL group, but not in the other two groups. Multivariate analysis showed that MCX11 IOLs were more prone to bending in highly myopic eyes with a smaller anterior capsular opening (β=0.236, p=0.023) and lower implanted power (β=0.542, p=0.001).

Conclusion In highly myopic eyes, IOLs with good capsular support show less backward bending, which result in a more stable lens position and refractive status postoperatively. Severe capsular contraction and low implanted power are risk factors for bending of certain IOLs.

  • treatment surgery
  • vision
  • imaging

Data availability statement

Data are available on reasonable request.

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Data availability statement

Data are available on reasonable request.

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Footnotes

  • YL and XZ contributed equally.

  • Contributors XZ designed the study. JQ, WH, KZ, DG and YD performed the study. JQ and DG performed data collection and management. JQ, WH and KZ performed data analysis and interpretation. JQ and YD cowrote the manuscript. XZ and YL critically revised the manuscript. JQ is guarantor.

  • Funding The publication of this article was supported by research grants from the National Natural Science Foundation of China (No.82122017, 82271069, 81870642, 81970780, 81670835 and 82101100), Science and Technology Innovation Action Plan of Shanghai Science and Technology Commission (No.19441900700 and No.21S31904900), Clinical Science and Technology Innovation Project of Shanghai Shenkang Hospital Development Center (No.SHDC12019X08 and SHDC2020CR4078), Double-E Plan of Eye & ENT Hospital (SYA202006), Shanghai Municipal Key Clinical Specialty Programme (shslczdzk01901).

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.