Article Text

Download PDFPDF
Identifying central 10° visual subfield associated with future worsening of visual acuity in eyes with advanced glaucoma

Abstract

Background/aims To determine a cluster of test points: visual subfield (VSF) of Humphrey Field Analyzer 10–2 test (HFA 10–2) of which baseline sensitivities were associated with future worsening of visual acuity (VA) in eyes with advanced glaucoma.

Methods A total of 175 advanced glaucoma eyes of 175 advanced glaucoma patients with well controlled intraocular pressure (IOP), a mean deviation of the Humphrey Field Analyzer 24–2 (HFA 24–2) test ≤ −20 decibels and best corrected VA ≥20/40, were included. At baseline, HFA 24–2 and HFA 10–2 tests were performed along with VA measurements. All patients underwent prospective follow-up of 5 years, and VA was measured every 6 months. The Cox proportional hazards model was used to identify visual field sensitivities associated with deterioration of VA and also blindness.

Results Deterioration of VA and blindness were observed in 15.4% and 3.4% of the eyes, respectively. More negative total deviation (TD) values in the temporal papillomacular bundle VSF were significantly associated with deterioration in VA. Averages of the TD values in this area of the HFA 10–2 test had the most predictive power of future VA deterioration (OR: 0.92, p<0.001). A very similar tendency was observed for blindness.

Conclusion In advanced glaucoma eyes with well-controlled IOP, careful attention is needed when the mean TD values in the temporal papillomacular bundle VSF, measured with a HFA 10–2 test is deteriorated. TD values of this VSF indicate higher risks for future deterioration of VA and also blindness.

  • Glaucoma

Data availability statement

No data are available.

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.