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Big bubble formation in deep anterior lamellar keratoplasty may be more successful in early keratoconus eyes
  1. Hyeck-Soo Son1,
  2. Uri Soiberman2
  1. 1University Eye Clinic Heidelberg, Heidelberg, Germany
  2. 2Cornea Division, Johns Hopkins Wilmer Eye Institute, Baltimore, Maryland, USA
  1. Correspondence to Dr Uri Soiberman; usoiber1{at}jhmi.edu

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The recent publication by Lucchino et al reports on preoperative predictive factors for big bubble (BB) formation during deep anterior lamellar keratoplasty (DALK) in keratoconus eyes.1 In a total of 140 eyes of 140 patients, the authors observed successful pneumatic dissection in 98 eyes (70.0%), with 94 type 1 BB (67.1%) and 4 type 2 BB (2.9%). The study provides topographic evidence for a higher BB success rate among earlier stages of keratoconus, as characterised by lower K-max, lower K-mean, higher corneal thickness at the thinnest point and lower difference in peripheral-minimal corneal thickness. Moreover, the anterior segment-optical coherence tomography (AS-OCT) classification2 was found to be the only factor that predicted BB formation, with mild to moderate keratoconus eyes, particularly those with no posterior stromal scars, demonstrating a greater likelihood of undergoing successful BB creation.

DALK is widely accepted as a preferred type of keratoplasty for anterior stromal pathologies such as keratoconus or scars.3 4 While achieving similar visual recovery …

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Footnotes

  • Contributors The senior author is the guarantor.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.

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