666 e-Letters

  • Re:Role of endothelial keretoplasty in penetrating keratoplasty graft rejection?
    Verinder S. Nirankari

    We thank Dr. Shoaib for his interest in our article.1 We agree that there are various causes of graft rejection and that performing an endothelial keratoplasty (EK) would not resolve the rejection. To clarify our wording for the article, patients who developed endothelial graft rejection with subsequent endothelial failure were offered EK under their penetrating keratoplasty (PK). The rejection episode was resolved at...

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  • Role of endothelial keretoplasty in penetrating keratoplasty graft rejection?
    Khawaja K Shoaib

    Article "Endothelial keratoplasty without Descemet's stripping in eyes with previous penetrating corneal transplants" by Nottage JM and Nirankari VS1, is very informative and the authors deserve appreciation for their wonderful work. However one point requires discussion. Authors mentioned that endothelial keratoplasty (EK) was done either for graft rejection (n = 9) or endothelial failure (n = 24). It seems logical to...

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  • CSR or TB?
    Khawaja K Shoaib

    The article "Oral rifampin utilisation for the treatment of chronic multifocal central serous retinopathy(CSR)"1 by Steinle NC et al is very informative. However a few points require further elaboration. We were told that patient is an African -American but for how long he stayed in Africa and how frequently he or any of his close family members visit any tuberculosis (TB) endemic area? As both CSR and ocular TB are poor...

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  • Re:Efficacy of Silicone Punctal Plugs in Children
    Khawaja K Shoaib

    A Mataftsi et al1 published an interesting article regarding punctal plugs in children. One of their aim was to establish the efficacy however they have not mentioned any test (Schirmer, Tear film break-up time, Rose Bengal staining, osmolarity) to confirm the diagnosis of dry eye and to calibrate the tear deficiency. It was only the clinical impression (flouresein staining is not specific for dry eyes and therefore cann...

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  • Switching anti-VEGFs in Tachyphylaxis
    Kopal Mithal

    Dear Editor,

    We read the article 'Bevacizumab and ranibizumab tachyphylaxis in the treatment of choroidal neovascularisation' with interest. We congratulate the authors for trying to establish the efficacy of a promising treatment strategy for Tachyphylaxis to Anti-VEGF drugs in Exudative AMD. We agree with the authors that this could be a useful option in patients who develop tachyphylaxis. However, there are s...

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  • Efficacy of Silicone Punctal Plugs in Children
    Mohammad J Ali

    We read with great interest the article by Mataftsi A et al.1 We congratulate the authors for providing insights into the use of punctal plugs in children. We would like to articulate a few of our observations. In seven cases where a secondary procedure was undertaken like a subconjunctival steroid injection or placement of contact lens, we believe these would be confounding...

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  • Potential Confounding factors
    Jignesh K Ved

    I would like to congratulate the authors for this wonderful effort, which throws some light on some of the time trends in the therapeutic area. However, while interpreting long term observational studies, some of the potential sources of bias should be kept in mind. One such potential confounding factor, is the observation of the end- points for Latanoprost, in the two distinct time-periods. The results for both the end-po...

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  • e-Iatrogenesis - the need for "error wisdom"
    John E A. Somner

    Simon Kelly is to be congratulated for his work to increase awareness of patient safety issues in ophthalmology. His studies analysing safety incidents recorded in the NPSA database have led to descriptions of incidents related to intravitreal injections and wrong lens insertion and suggestions on how to improve patient safety. Many of the patient safety incidents analysed resulted from poor documentation described in the...

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  • Response
    Malik Y Kahook

    We would like to thank Zaidi et al. for their interest in our publication titled, "Sustained elevation of intraocular pressure after intravitreal injections of anti-VEGF agents." [1] As stated in our publication, we believe anti-VEGF agents revolutionized the treatment of ocular neovascular disease and their overall safety profile is excellent. The points by Zaidi et al. are valid and we take this opportunity to expand...

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  • respond
    Vannarut Satitpitakul

    In your September 2010 issue, I read with interest the article about amblyopia by D J Hwang.1 The group has also previously published a similar article in Korean Journal of Ophthalmology 2 but it was not mentioned in the references. Both articles included their participants from the same hospital since 2000 and the eligibility criteria were nearly identical. I was wondering if both articles share the same group of parti...

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