eLetters

128 e-Letters

published between 2006 and 2009

  • Intraocular pressure rise during dilatation
    Nathan M. Radcliffe

    Dear Editor

    We read with great interest a recent report by Siam et al., “The amount of intraocular pressure rise during pharmacological pupillary dilatation is an indicator of the likelihood of future progression of glaucoma.” These authors report that the likelihood of optic nerve progression (defined by the disc damage likelihood scale, the glaucoma staging system 2, or both) in open angle patients is related t...

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  • Bevacizumab for polypoidal vasculopathy should be evaluated in a cross cultural population
    Shree K Kurup

    Dear Editors

    We read with great interest, the illuminating article by Drs Gomi, Sawa and Tano. Our limited experience (4 Afro-American patients) with intravitreal bevacizumab (IVB) for polypoidal vasculopathy (PPV) has been more positive.

    We had reported the first success early this year in terms of lasting remission [1]. Furthermore, I enclose details on another patient who had PPV OU, in all likeliho...

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  • Cost effectiveness of cataract surgery
    Ediriweera Desapriya

    Dear Editor

    According to the Canadian Community Health Survey, approximately 82% of the population of seniors aged 65 – 80+ (3,000,000 seniors) reported having vision problems in Canada. [1] Cataracts are the leading cause of vision impairment among seniors. Between the period of 1994 – 2003, proportions of seniors with cataracts rose from 14% – 20% with populations aged 75 and over accounting for higher percentage...

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  • Tobacco alcohol amblyopia - Authors reply
    Raed Behbehani

    Dear Editor

    We appreciate the comments of Grzybowski et al. about our article. We agree that the term "tobacco alcohol amblyopia" is not very accurate and does not specifically describe the underlying cause of vision loss. It may also not fit the "historic" description of the condition. However, the term is still used widely to describe a spectrum characterized by optic nerve dysfunction and selective involvement of...

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  • Cataract surgery in England
    Simon P Kelly

    Dear Editor

    We read with interest the paper by Keenan [ref 1] and colleagues.

    We recently studied the 2005/06 Hospital Episode Statistics (HES) data for cataract and have reached similar conclusions. We agree with the authors’ observations that as NHS cataract surgery rates (CSRs) in England have increased significantly in recent years, several questions are now raised. What is the appropriate CSR in a d...

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  • Use of Avastin in rat models: Comments.
    Yuksel Totan

    Dear Editor

    We have read Manzano et al’s insightful paper[1] with interest and appreciated the comments concerning the inhibitory effects of bevacizumab on corneal neovascularisation (NV). However, the manuscript had some important aspects that need to be clarified. Cumulative data from numerous basic and clinical studies strongly implicates the central role of VEGF in ocular and corneal angiogenesis. Binding all free-ci...

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  • Vitamin A deficiency and possible link with colobomatous malformations
    Stella J Hornby

    Dear Editor

    We read with interest the letter by Decock et al regarding the rare congenital ocular malformation (orbital cyst and bilateral colobomatous microphthalmos). [1]

    The female child reported was the product of a mother with documented vitamin A deficiency (VAD) during the second trimester of pregnancy after previous gastric bypass surgery for morbid obesity. The authors do not report the sympto...

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  • Was it really tobacco alcohol-amblyopia ?
    Andrzej Grzybowski

    Dear Editor,

    Further to the article of Behbehani R, Sergott RC and Savino PJ Tobacco-alcohol amblyopia: a maculopathy? [1], we question whether either patient had tobacco-alcohol amblyopia (TAA).

    “TAA” occurs in patients with high alcohol and tobacco intake, but is perhaps a misnomer with “nutritional optic neuropathy” being more appropriate. Many such patients are nutritionally deficient consequent u...

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  • Bimatoprost, the prodrug of a prostaglandin analog
    Carl B Camras

    Dear Editor,

    We congratulate the authors of their adequately designed study(1) that demonstrates the high concentration of the free acid (the product of hydrolysis) of bimatoprost (BP), an amide, in the aqueous humor of patients receiving a single drop of BP 1, 3, or 6 hours prior to cataract surgery. This important study confirms the results found in previous studies.(2,3) However, despite providing important confirmat...

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  • Bevacizumab and rodent VEGF
    Jing Hua

    Dear Editor,

    We read with interest the recently published paper by Manzano et al. titled ‘Inhibition of experimental corneal neovascularisation by bevacizumab (Avastin)’. The authors used topical eyedrop application of either saline or bevacizumab in a rat model of corneal neovascularization, with apparent moderate success. Furthermore, in their discussion, they mention that there was incomplete inhibition of th...

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