106 e-Letters

published between 2013 and 2016

  • Outer retinal tubulation is a process of neurodegeneration
    Katie M. Litts, BS

    We read with interest the report by Espina et al(1) regarding changes occurring in outer retinal tubulation (ORT) during the course of intravitreal anti-VEGF treatment.(2) These authors retrospectively describe ORT changes observed during and after anti-VEGF treatment and correlated these changes to disease activity or presence of retinal fluid in 31 patients with neovascular age-related macular degeneration (AMD) with...

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  • Treat-and-Extend regimen for diabetic macular oedema: Considerations from real medicine.
    Fernando Lopez-Herrero

    Dear Editor, After reading the article entitled "Ranibizumab 0,5 Treat-and-Extend regimen for diabetic macular oedema: the RETAIN study" by Prunte et al (1), there are several considerations that we would like to bring to your attention. From the data provided, we noticed how 48.3% of patients in the "pro re nata" (PRN) regime required <=9 injections over a two-year period. On the other hand, this condition in "treat...

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  • Re:Non-mydriatic fundus photography in epidemiological prevalence studies
    Kwadwo Owusu Akuffo
    We would like to thank Craig et al for their interest in our article.[1] TILDA was designed to provide accurate and reliable information regarding ageing in the Republic of Ireland in order to inform policy. Ophthalmic assessment, which included retinal photography, was a small component of the broader TILDA study. 1. We agree with Craig et al that mydriatic photography is preferable, when attempting to identify and grade age-rel...
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  • Re:Orbital lymphatic malformation may shrink with treatment of anaemia
    Alex Barnacle

    The authors thank Mr Moreker for his letter regarding our series. We agree that these are often complex cases and that each patient should be assessed holistically and discussed individually, ideally in a multidisciplinary setting. We do not check haemoglobin levels in all the patients referred to us, in part because severe anaemia in otherwise well children is rare in the UK population, but we agree that this should be...

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  • Comment: Evaluation of Choroidal Thickness in Retinitis Pigmentosa Using Enhanced Depth Imaging Optical Coherence Tomography
    Onder Ayyildiz

    Dear Editor, We read the article entitled ''Evaluation of choroidal thickness in retinitis pigmentosa using enhanced depth imaging optical coherence tomography'' by Dilsher S. Dhoot and associates (1), and would like to offer our comments. The authors presented, in this prospective, case- control study of choroidal imaging with enhanced depth imaging spectral domain optical coherence tomography in patients with retinitis...

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  • Disagreement on Limits of Agreement
    Andrew Carkeet
    Dear Editor, I read, with interest, the article entitled: Validity and repeatability of the Aladdin ocular biometer [1] and it appears to contain errors in the reporting of Bland-Altman 95% Limits of Agreement (LoAs). Figures 1,2 and 3 all contain the following statement in their legends: "The dotted lines represent the upper and lower 95% limits of agreement." These statements are, I believe, incorrect. The "dotted lines" are c...
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  • Non-mydriatic fundus photography in epidemiological prevalence studies
    Craig Wilde

    We read with interest the article by Akuffo et al reporting the prevalence of age related macular degeneration (AMD) in the Republic of Ireland and congratulate them on their findings. The authors report a recent meta-analysis demonstrating considerable heterogeneity in the prevalence of AMD across studies of European ancestry (1), with 20% variability being explained by the age-ranges used and 50% by study characterist...

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  • Significance of hyper auto fluorescent (HAF) ring in choroidal neovascularization (CNV) in Age related Macular Degeneration (AMD)
    Pradeep Sagar

    Dear editor

    We read the article titled, "Significance of the hyperautofluorescent ring associated with choroidal neovascularization in eyes undergoing anti- VEGF therapy for wet age-related macular degeneration"[1] with great interest. Our paper "Evaluation of fundus autofluorescence patterns in Age -related Macular Degeneration" is presently under review. After reading the above article we retrospectively analyze...

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  • Orbital lymphatic malformation may shrink with treatment of anaemia
    Sunil R Moreker

    The large single center experience of Barnacle et al does convince one of the need to use sclerotherapy and withhold surgery in such cases. But lymphatic malformations are the most varied in terms of presentations. Each malformation is different and it is not possible to club the various kinds of seemingly one type of malformations ,together, in one group ; nor would it be possible to state which modality should be fi...

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  • Re:Trephination size and success of big-bubble formation in deep anterior lamellar keratoplasty for keratoconus.
    Dr. Sepehr Feizi

    We would like to acknowledge our appreciation for Dr. Peyman for paying close attention to our article and raising important points. Now, big-bubble deep anterior lamellar keratoplasty (DALK) is a corneal transplantation technique of choice for corneal stromal pathologies not involving endothelium such as keratoconus. The principle shortcoming of this technique is that it is technically challenging. Any attempts to incr...

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