eLetters

89 e-Letters

published between 2007 and 2010

  • Was it really tobacco alcohol-amblyopia ?
    Andrzej Grzybowski

    Dear Editor,

    Further to the article of Behbehani R, Sergott RC and Savino PJ Tobacco-alcohol amblyopia: a maculopathy? [1], we question whether either patient had tobacco-alcohol amblyopia (TAA).

    “TAA” occurs in patients with high alcohol and tobacco intake, but is perhaps a misnomer with “nutritional optic neuropathy” being more appropriate. Many such patients are nutritionally deficient consequent u...

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  • Bimatoprost, the prodrug of a prostaglandin analog
    Carl B Camras

    Dear Editor,

    We congratulate the authors of their adequately designed study(1) that demonstrates the high concentration of the free acid (the product of hydrolysis) of bimatoprost (BP), an amide, in the aqueous humor of patients receiving a single drop of BP 1, 3, or 6 hours prior to cataract surgery. This important study confirms the results found in previous studies.(2,3) However, despite providing important confirmat...

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  • Bevacizumab and rodent VEGF
    Jing Hua

    Dear Editor,

    We read with interest the recently published paper by Manzano et al. titled ‘Inhibition of experimental corneal neovascularisation by bevacizumab (Avastin)’. The authors used topical eyedrop application of either saline or bevacizumab in a rat model of corneal neovascularization, with apparent moderate success. Furthermore, in their discussion, they mention that there was incomplete inhibition of th...

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  • Avastin effect on the optic nerve
    Sherif AK Amer

    Dear Editor

    The rising use of Avastin injection for choroidal neovascular membranes and other conditions has been successful in preliminary reports. However, I have experienced 5 cases with optic neuropathy following Avastin injection after an interval of 2-4 months. Although my number of cases is very small, it suggests that a study be conducted to investigate the effect of intravitreal Avastin on the optic nerve u...

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  • Retinal and subdural haemorrhages from minor falls?
    Horace B Gardner

    Dear Editor

    I wish to thank Ganesh et al for confirming (p <0.001) the marked and obvious difference between the age distribution of retinal and subdural haemorrhages in America and Japan. Finding this difference "not surprising" neither negates nor explains it. More sophisticated child abuse teams could not discover cases in Japan months before they occur. Variations in incidence of osteogenesis imperfecta wou...

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  • Authors reply to the letter written by Wang JJ, concerning the Beijing Eye Study Report
    Jost B. Jonas

    Dear Editor

    The authors would like to thank Dr. J.J. Wang for her constructive comments about the statistical analysis of the data obtained in the Beijing Eye Study.[1] As already pointed out in another recent reply to a letter by Dr. Wang, the authors became aware of the limitations in their statistical analysis of the data of the Beijing Eye Study.[2] The authors are grateful to Dr. Wang for clarifying these wea...

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  • The Beijing Eye Study Report
    Jie Jin Wang

    Dear Editor,

    I read with interest the report from the Beijing Eye Study by Xu, et al. published in BJO last year (BJO 2006;90:1087-1090), titled: Associated factors for age related maculopathy in the adult population in China: the Beijing Eye Study.

    In the abstract, Results and Table 1 of this report, some association estimates are provided as p values and 95% confidence intervals without point estimate...

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  • Analytic model for central corneal thickness and correlation to disc size
    Afshin Parsa

    Dear Editor

    We thank Dr. Holló [1] for his comments and the opportunity to elaborate further on our findings. We had considered the point that both eyes from an individual may not be fully independent from one another. As such, in our initial analysis, we calculated the Pearson’s correlation coefficient (r) between left and right eyes for both of our measures. We found the central corneal thickness (CCT) between...

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  • High incidence of vitreomacular traction in recurrent choroidal neovascularisation after repeated ph
    DR GITUMONI SHARMA

    Dear Editor

    After going through the above mentioned scientific report, I have some queries and suggestions as mentioned below:

    1. Is a surgeon's opinion enough to declare a case as having Vitreomacular traction as mentioned in this study? Or is a definite documentation possible with aid like OCT?

    2. In 2 cases, single sessions of PDT were done, which does not match the criterion of repeated...

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  • Scratch assay measures cell migration rather than cell proliferation
    Rajesh K Sharma

    Dear Editor,

    We read the paper titled “Anti-permeability and anti-proliferative effects of standard and frozen bevacizumab on choroidal endothelial cells” by Peters et al [1] in Br J Ophthalmol. Dec. 2006 issue with great interest. There are a number of issues that we would like to point out with regards to the methodology. The authors have solely used scratch assay in the presence of 50ng/ml VEGF +- 0.5mg/ml b...

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