PT  - JOURNAL ARTICLE
AU  - J Zervas
AU  - G Tsokos
AU  - G Papadakis
AU  - E Kabouklis
AU  - D Papadopoulos
TI  - HLA-B27 frequency in Greek patients with acute anterior uveitis.
AID  - 10.1136/bjo.61.11.699
DP  - 1977 Nov 01
TA  - British Journal of Ophthalmology
PG  - 699--701
VI  - 61
IP  - 11
4099  - http://bjo.bmj.com/content/61/11/699.short
4100  - http://bjo.bmj.com/content/61/11/699.full
SO  - Br J Ophthalmol1977 Nov 01; 61
AB  - The histocompatibility antigen HLA-B27 was identified in 12 out of 33 patients with acute non-granulomatous anterior uveitis. This is a frequency of 36.36%, compared with 4.72% in controls. Seven patients had in addition evidence of systemic disease, including ankylosing spondylitis, sacroiliitis, Reiter's disease, Still's disease, and rheumatoid arthritis. Five of these were HLA-B27 positive, which suggests that the uveitis in many of these cases has a similar aetiology to the uveitis in those with rheumatic disease. It appears that the more severe cases of acute anterior uveitis are related more frequently to the presence of HLA-B27.