RT Journal Article
SR Electronic
T1 HLA-B27 frequency in Greek patients with acute anterior uveitis.
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 699
OP 701
DO 10.1136/bjo.61.11.699
VO 61
IS 11
A1 J Zervas
A1 G Tsokos
A1 G Papadakis
A1 E Kabouklis
A1 D Papadopoulos
YR 1977
UL http://bjo.bmj.com/content/61/11/699.abstract
AB The histocompatibility antigen HLA-B27 was identified in 12 out of 33 patients with acute non-granulomatous anterior uveitis. This is a frequency of 36.36%, compared with 4.72% in controls. Seven patients had in addition evidence of systemic disease, including ankylosing spondylitis, sacroiliitis, Reiter's disease, Still's disease, and rheumatoid arthritis. Five of these were HLA-B27 positive, which suggests that the uveitis in many of these cases has a similar aetiology to the uveitis in those with rheumatic disease. It appears that the more severe cases of acute anterior uveitis are related more frequently to the presence of HLA-B27.