RT Journal Article
SR Electronic
T1 A double-blind comparison of topical therapy of chlamydial ocular infection (TRIC infection) with rifampicin or chlortetracycline.
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 549
OP 552
DO 10.1136/bjo.65.8.549
VO 65
IS 8
A1 S. Darougar
A1 N. Viswalingam
A1 H. El-Sheikh
A1 P. A. Hunter
A1 P. Yearsley
YR 1981
UL http://bjo.bmj.com/content/65/8/549.abstract
AB A double-blind stratified trial was carried out on 85 patients to assess the efficacy of topical therapy with 1% chlortetracycline eye ointment in comparison with 1% rifampicin eye ointment in the treatment of chlamydial ocular infection of sexually transmitted origin (paratrachoma). Patients included were selected on the basis of positive culture for Chlamydia trachomatis. A 6-week course of treatment with chlortetracycline or rifampicin 3 times daily gave a clinical cure rate of 80% and 75% and a microbiological cure rate of 93% and 86% respectively. In patients who were not cured the intensity of inflammatory responses was considerably reduced.