RT Journal Article
SR Electronic
T1 Exogenous ocular candidiasis associated with intravenous heroin abuse.
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 841
OP 845
DO 10.1136/bjo.68.11.841
VO 68
IS 11
A1 T. C. Sorrell
A1 C. Dunlop
A1 P. J. Collignon
A1 J. A. Harding
YR 1984
UL http://bjo.bmj.com/content/68/11/841.abstract
AB Seven young men developed disseminated candidiasis within 10 days of a single episode of intravenous heroin abuse. Sequential development of eye and skin lesions was noted in all cases. The bone or costal cartilage was involved in five. Ocular manifestations of candidiasis included episcleritis, chorioretinitis, and endophthalmitis. A presumptive diagnosis of candida chorioretinitis was established rapidly by culture of Candida albicans from involved skin and costal cartilage. Systemic therapy with amphotericin B plus 5-fluorocytosine resulted in cure of the episcleritis, chorioretinitis, osteomyelitis, costochondritis, and skin infection. Pars plana vitrectomy with local instillation of amphotericin B was required to cure chorioretinitis associated with vitreal extension of infection.