PT  - JOURNAL ARTICLE
AU  - J Chess
AU  - D M Albert
AU  - A R Bellows
AU  - R Dallow
TI  - Uveal melanoma: case report of extension through the optic nerve to the surgical margin in the orbital apex.
AID  - 10.1136/bjo.68.4.272
DP  - 1984 Apr 01
TA  - British Journal of Ophthalmology
PG  - 272--275
VI  - 68
IP  - 4
4099  - http://bjo.bmj.com/content/68/4/272.short
4100  - http://bjo.bmj.com/content/68/4/272.full
SO  - Br J Ophthalmol1984 Apr 01; 68
AB  - An unsuspected uveal melanoma arising in a phthisical eye extended through the optic nerve to the surgical margin in the orbital apex without involvement of other orbital structures. Step sections showed the continuous extension through the nerve. Factors likely to predispose to optic nerve extension include epithelioid cell type, large tumour size, peripapillary involvement, and glaucoma. Optic nerve extension carries the risks noted with orbital extension of intraocular tumour, but may in addition lead more directly to intracranial invasion, including a chiasmal syndrome. The role of exenteration and radiotherapy in these cases remains uncertain.