RT Journal Article
SR Electronic
T1 Uveal melanoma: case report of extension through the optic nerve to the surgical margin in the orbital apex.
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 272
OP 275
DO 10.1136/bjo.68.4.272
VO 68
IS 4
A1 J Chess
A1 D M Albert
A1 A R Bellows
A1 R Dallow
YR 1984
UL http://bjo.bmj.com/content/68/4/272.abstract
AB An unsuspected uveal melanoma arising in a phthisical eye extended through the optic nerve to the surgical margin in the orbital apex without involvement of other orbital structures. Step sections showed the continuous extension through the nerve. Factors likely to predispose to optic nerve extension include epithelioid cell type, large tumour size, peripapillary involvement, and glaucoma. Optic nerve extension carries the risks noted with orbital extension of intraocular tumour, but may in addition lead more directly to intracranial invasion, including a chiasmal syndrome. The role of exenteration and radiotherapy in these cases remains uncertain.