RT Journal Article SR Electronic T1 Experimental model of proliferative vitreoretinopathy (PVR) in the vitrectomised eye: effect of silicone oil. JF British Journal of Ophthalmology JO Br J Ophthalmol FD BMJ Publishing Group Ltd. SP 332 OP 335 DO 10.1136/bjo.68.5.332 VO 68 IS 5 A1 J S Lean A1 W A van der Zee A1 S J Ryan YR 1984 UL http://bjo.bmj.com/content/68/5/332.abstract AB Silicone oil alone or as an adjunct to vitrectomy is widely used for the treatment of retinal detachment complicated by proliferative vitreoretinopathy (PVR). It appears to reduce the tendency for recurrent traction detachment, but the mechanism of this action is obscure. We have studied the effects of silicone oil in an experimental animal model. Twenty five thousand homologous fibroblasts were injected into the aphakic vitrectomised rabbit eye, and traction detachment of the vascularised retina (medullary rays) regularly resulted. Intraocular silicone oil did not influence the development of this experimental detachment.