PT  - JOURNAL ARTICLE
AU  - K. R. Alexander
AU  - G. A. Fishman
TI  - Supernormal scotopic ERG in cone dystrophy.
AID  - 10.1136/bjo.68.2.69
DP  - 1984 Feb 01
TA  - British Journal of Ophthalmology
PG  - 69--78
VI  - 68
IP  - 2
4099  - http://bjo.bmj.com/content/68/2/69.short
4100  - http://bjo.bmj.com/content/68/2/69.full
SO  - Br J Ophthalmol1984 Feb 01; 68
AB  - Three patients with a bull's-eye macular lesion and other signs characteristic of cone dystrophy gave an unusual ERG finding. In response to a white flash of moderate intensity the scotopic b-wave amplitude was considerably larger than normal. One patient had elevated rod thresholds and nyctalopia, while the other 2 had normal rod sensitivity associated with the supernormal scotopic b-wave amplitude. In the latter 2 patients the abnormal ERG pattern was unchanged for 4 years and 7 years respectively. This atypical finding, of a supernormal scotopic b-wave amplitude in response to light of moderate intensity, appears to characterise a subgroup of patients with cone dystrophy, probably of autosomal recessive inheritance. The pathogenesis of the abnormal ERG remains uncertain.