RT Journal Article
SR Electronic
T1 A genetic linkage study of a kindred with X-linked retinitis pigmentosa.
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 340
OP 347
DO 10.1136/bjo.69.5.340
VO 69
IS 5
A1 S S Bhattacharya
A1 J F Clayton
A1 P S Harper
A1 G W Hoare
A1 M R Jay
A1 A L Lyness
A1 A F Wright
YR 1985
UL http://bjo.bmj.com/content/69/5/340.abstract
AB A large kindred with X-linked retinitis pigmentosa (XLRP) was investigated clinically and by means of genetic linkage with a view to developing methods of carrier detection and early diagnosis. A restriction fragment length polymorphism, identified by recombinant DNA probe L1.28, showed close genetic linkage to XLRP in this kindred and is a potentially useful marker for the purposes of genetic counselling.