PT - JOURNAL ARTICLE AU - P Runge AU - D P Muller AU - J McAllister AU - D Calver AU - J K Lloyd AU - D Taylor TI - Oral vitamin E supplements can prevent the retinopathy of abetalipoproteinaemia. AID - 10.1136/bjo.70.3.166 DP - 1986 Mar 01 TA - British Journal of Ophthalmology PG - 166--173 VI - 70 IP - 3 4099 - http://bjo.bmj.com/content/70/3/166.short 4100 - http://bjo.bmj.com/content/70/3/166.full SO - Br J Ophthalmol1986 Mar 01; 70 AB - Six patients with abetalipoproteinaemia are described who received large doses of oral vitamin E for between 12 and 18 years in addition to a low fat diet and supplements of the other fat soluble vitamins. The progressive retinopathy observed in untreated abetalipoproteinaemia was substantially modified and most probably prevented by this therapy. Angioid streaks were noted in one patient. Treatment with vitamin A alone did not prevent or arrest the progression of the retinal lesion.