RT Journal Article SR Electronic T1 Bilateral ocular disease as the initial presentation of malignant lymphoma. JF British Journal of Ophthalmology JO Br J Ophthalmol FD BMJ Publishing Group Ltd. SP 248 OP 252 DO 10.1136/bjo.72.4.248 VO 72 IS 4 A1 R. Weisenthal A1 W. C. Frayer A1 C. W. Nichols A1 R. C. Eagle YR 1988 UL http://bjo.bmj.com/content/72/4/248.abstract AB Malignant lymphocytic lymphoma rarely involves the eye. In two patients we found ocular signs and symptoms as the initial presentation of systemic disease. In the first patient periorbital swelling and ptosis of one year's duration ultimately proved to be the result of malignant lymphoma. After resolution of swelling and ptosis with chemotherapy, the patient returned with diffuse iris involvement and uveitis with a hypopyon. In the second patient an acute change of refractive error proved to be the result of a lymphomatous deposit in the choroid. In both instances common symptoms were the initial manifestations of a diffuse malignant disease.