PT  - JOURNAL ARTICLE
AU  - P. McKenna
AU  - S. J. Morgan
AU  - R. C. Bosanquet
AU  - M. F. Laker
TI  - A case of cerebrotendinous xanthomatosis. II: The sterol content of a cataractous lens.
AID  - 10.1136/bjo.74.10.629
DP  - 1990 Oct 01
TA  - British Journal of Ophthalmology
PG  - 629--630
VI  - 74
IP  - 10
4099  - http://bjo.bmj.com/content/74/10/629.short
4100  - http://bjo.bmj.com/content/74/10/629.full
SO  - Br J Ophthalmol1990 Oct 01; 74
AB  - The cholestanol content of a cataractous lens nucleus from a patient with cerebrotendinous xanthomatosis (CTX) was quantified by gas chromatography-mass spectrometry and found to be 0.27 micrograms per mg freeze-dried lens tissue. The cholestanol-cholesterol ratio of 1.7% in the lens nucleus was similar to that in the serum of the CTX patient. The cholestanol content and cholestanol-cholesterol ratio in the CTX lens were approximately four-fold and six-fold greater respectively than the mean levels found in three senile cataractous lens nuclei analysed simultaneously for comparative purposes.