TY - JOUR T1 - Bromovinyldeoxyuridine and interferon treatment in ulcerative herpetic keratitis: a double masked study. JF - British Journal of Ophthalmology JO - Br J Ophthalmol SP - 604 LP - 607 DO - 10.1136/bjo.73.8.604 VL - 73 IS - 8 AU - O P van Bijsterveld AU - P J Meurs AU - E de Clercq AU - P C Maudgal Y1 - 1989/08/01 UR - http://bjo.bmj.com/content/73/8/604.abstract N2 - Bromovinyldeoxyuridine is a potent and safe antiherpes compound that in combination with a placebo treatment promoted the partial and complete healing of herpetic epithelial disease in 22 patients in average times of 4-6 days and 8.5 days respectively. However, when BVDU was combined with 1.5 X 10(6) IU of recombinant a 2C interferon, partial and complete healing times for keratitis in 19 patients were reduced to 2-6 days and 4-6 days respectively. No toxic effects of the medications were observed in any patient. ER -