RT Journal Article
SR Electronic
T1 Bromovinyldeoxyuridine and interferon treatment in ulcerative herpetic keratitis: a double masked study.
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 604
OP 607
DO 10.1136/bjo.73.8.604
VO 73
IS 8
A1 O P van Bijsterveld
A1 P J Meurs
A1 E de Clercq
A1 P C Maudgal
YR 1989
UL http://bjo.bmj.com/content/73/8/604.abstract
AB Bromovinyldeoxyuridine is a potent and safe antiherpes compound that in combination with a placebo treatment promoted the partial and complete healing of herpetic epithelial disease in 22 patients in average times of 4-6 days and 8.5 days respectively. However, when BVDU was combined with 1.5 X 10(6) IU of recombinant a 2C interferon, partial and complete healing times for keratitis in 19 patients were reduced to 2-6 days and 4-6 days respectively. No toxic effects of the medications were observed in any patient.