RT Journal Article
SR Electronic
T1 Fundus changes in (type II) mesangiocapillary glomerulonephritis simulating drusen: a histopathological report.
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 297
OP 302
DO 10.1136/bjo.73.4.297
VO 73
IS 4
A1 J Duvall-Young
A1 M K MacDonald
A1 N M McKechnie
YR 1989
UL http://bjo.bmj.com/content/73/4/297.abstract
AB We report for the first time to our knowledge the histopathological findings in the eye of a patient with type II mesangiocapillary glomerulonephritis (dense deposit disease) in which a deposit of material morphologically very similar to that which is pathognomonic for the disease in the kidney was demonstrated in Bruch's membrane. The nature of the deposit in the renal lesion is unknown but is considered to represent a structural alteration secondary to a reaction with anticomplement antibody. Clinically the fundus appearance resembled that seen in drusen.