PT  - JOURNAL ARTICLE
AU  - H. S. Dua
AU  - A. McKinnon
AU  - P. G. McMenamin
AU  - J. V. Forrester
TI  - Ultrastructural pathology of the 'barrier sites' in experimental autoimmune uveitis and experimental autoimmune pinealitis.
AID  - 10.1136/bjo.75.7.391
DP  - 1991 Jul 01
TA  - British Journal of Ophthalmology
PG  - 391--397
VI  - 75
IP  - 7
4099  - http://bjo.bmj.com/content/75/7/391.short
4100  - http://bjo.bmj.com/content/75/7/391.full
SO  - Br J Ophthalmol1991 Jul 01; 75
AB  - Lewis rats were immunised with retinal S-antigen to induce experimental autoimmune uveitis and experimental autoimmune pinealitis. The blood-retinal and blood-pineal 'barrier sites' were examined by transmission electron microscopy. Inflammatory cell movement through Bruch's membrane involved separation of its constituent layers, cell migration through pores in the membrane, and between retinal pigment epithelial cells without causing significant displacement of the retinal pigment epithelial cell layer. The endothelial cells of retinal and pineal vessels with perivascular infiltrates showed morphological features resembling endothelium of 'high endothelial venules'.