PT  - JOURNAL ARTICLE
AU  - A Karma
AU  - T A Pirttilä
AU  - M K Viljanen
AU  - Y E Lähde
AU  - C M Raitta
TI  - Secondary retinitis pigmentosa and cerebral demyelination in Lyme borreliosis.
AID  - 10.1136/bjo.77.2.120
DP  - 1993 Feb 01
TA  - British Journal of Ophthalmology
PG  - 120--122
VI  - 77
IP  - 2
4099  - http://bjo.bmj.com/content/77/2/120.short
4100  - http://bjo.bmj.com/content/77/2/120.full
SO  - Br J Ophthalmol1993 Feb 01; 77
AB  - A 15-year-old girl developed retinitis pigmentosa-like fundus changes in the left eye and optic neuropathy in the right eye as well as cerebral demyelination as a result of late Lyme borreliosis (LB). The diagnosis was confirmed by polymerase chain reaction, which detected a Borrelia burgdorferi specific segment of a gene coding for 41 kD endoflagellin, both in the vitreous and the cerebrospinal fluid. The diagnosis was delayed because testing for Borrelia antibodies in serum and cerebrospinal fluid yielded negative results. However, later on, another laboratory reported the antibodies of the patient's pretreatment serum to be positive for LB.