PT  - JOURNAL ARTICLE
AU  - Goggin, M
AU  - O'Keefe, M
AU  - Hughes, H
TI  - Two cases of coloboma associated with unbalanced translocations.
AID  - 10.1136/bjo.77.2.122
DP  - 1993 Feb 01
TA  - British Journal of Ophthalmology
PG  - 122--123
VI  - 77
IP  - 2
4099  - http://bjo.bmj.com/content/77/2/122.short
4100  - http://bjo.bmj.com/content/77/2/122.full
SO  - Br J Ophthalmol1993 Feb 01; 77
AB  - Two cases of coloboma are recorded, both secondary to previously unreported unbalanced translocations. These cases underline the association of chromosomal abnormalities and coloboma, particularly when accompanied by systemic abnormalities. They also highlight the importance of a full systemic assessment of coloboma patients and adequate genetic counselling for both patients and their families.