PT  - JOURNAL ARTICLE
AU  - Baca, W
AU  - Fishman, G A
AU  - Alexander, K R
AU  - Glenn, A M
TI  - Dark adaptation in patients with Best vitelliform macular dystrophy.
AID  - 10.1136/bjo.78.6.430
DP  - 1994 Jun 01
TA  - British Journal of Ophthalmology
PG  - 430--432
VI  - 78
IP  - 6
4099  - http://bjo.bmj.com/content/78/6/430.short
4100  - http://bjo.bmj.com/content/78/6/430.full
SO  - Br J Ophthalmol1994 Jun 01; 78
AB  - Psychophysical dark adaptation studies were performed in six patients with Best vitelliform macular dystrophy (BVMD) using a Goldmann-Weekers dark adaptometer. Prebleach thresholds were determined before obtaining a postbleach full recovery curve. Unlike patients with Stargardt macular dystrophy, all patients with BVMD showed a normal time to reach their baseline dark adapted thresholds after bleaching of their rod visual pigment when tested in clinically normal appearing retina. Although a lipofuscin material accumulates within retinal pigment epithelial cells in patients with either Best or Stargardt dystrophy, functional findings pertaining to recovery of rod dark adaptation thresholds as well as electro-oculogram light peak to dark trough ratios are different in these two disorders.