TY - JOUR T1 - Dark adaptation in patients with Best vitelliform macular dystrophy. JF - British Journal of Ophthalmology JO - Br J Ophthalmol SP - 430 LP - 432 DO - 10.1136/bjo.78.6.430 VL - 78 IS - 6 AU - W Baca AU - G A Fishman AU - K R Alexander AU - A M Glenn Y1 - 1994/06/01 UR - http://bjo.bmj.com/content/78/6/430.abstract N2 - Psychophysical dark adaptation studies were performed in six patients with Best vitelliform macular dystrophy (BVMD) using a Goldmann-Weekers dark adaptometer. Prebleach thresholds were determined before obtaining a postbleach full recovery curve. Unlike patients with Stargardt macular dystrophy, all patients with BVMD showed a normal time to reach their baseline dark adapted thresholds after bleaching of their rod visual pigment when tested in clinically normal appearing retina. Although a lipofuscin material accumulates within retinal pigment epithelial cells in patients with either Best or Stargardt dystrophy, functional findings pertaining to recovery of rod dark adaptation thresholds as well as electro-oculogram light peak to dark trough ratios are different in these two disorders. ER -