RT Journal Article
SR Electronic
T1 Dark adaptation in patients with Best vitelliform macular dystrophy.
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 430
OP 432
DO 10.1136/bjo.78.6.430
VO 78
IS 6
A1 W Baca
A1 G A Fishman
A1 K R Alexander
A1 A M Glenn
YR 1994
UL http://bjo.bmj.com/content/78/6/430.abstract
AB Psychophysical dark adaptation studies were performed in six patients with Best vitelliform macular dystrophy (BVMD) using a Goldmann-Weekers dark adaptometer. Prebleach thresholds were determined before obtaining a postbleach full recovery curve. Unlike patients with Stargardt macular dystrophy, all patients with BVMD showed a normal time to reach their baseline dark adapted thresholds after bleaching of their rod visual pigment when tested in clinically normal appearing retina. Although a lipofuscin material accumulates within retinal pigment epithelial cells in patients with either Best or Stargardt dystrophy, functional findings pertaining to recovery of rod dark adaptation thresholds as well as electro-oculogram light peak to dark trough ratios are different in these two disorders.