RT Journal Article SR Electronic T1 Cataract progression in India JF British Journal of Ophthalmology JO Br J Ophthalmol FD BMJ Publishing Group Ltd. SP 896 OP 900 DO 10.1136/bjo.81.10.896 VO 81 IS 10 A1 M Srinivasan A1 Rahim Rahmathullah A1 Clifford R Blair A1 Aparna C Murphy A1 Roy W Beck A1 John H Wilkins A1 John P Whitcher A1 Gilbert Smolin YR 1997 UL http://bjo.bmj.com/content/81/10/896.abstract AB AIMS The study was undertaken to test the feasibility of using the LOCS III cataract grading scale in the field and to determine the rate of cataract progression over a 1 year period of time. METHODS For 150 subjects between the ages of 33 and 55 who attended the refraction clinic at Aravind Eye Hospital in Madurai, India, lens abnormalities were graded at the slit lamp using the LOCS III scale. One year later, 99 of the subjects were re-evaluated by the same methodology to assess the amount of lens change. RESULTS Interrater reliability was high. A change of 0.5 or more in lens colour, cortical, nuclear, or posterior subcapsular cataract was observed in at least one eye of 54% of the subjects. CONCLUSION The LOCS III grading scale is a feasible method for measuring lens changes in the field with the slit lamp. Cataract progression in India is rapid enough to permit intervention studies to be performed with relatively small numbers of subjects over a short period of time (that is, 600 subjects for 2 years).