PT - JOURNAL ARTICLE AU - T F W McMullan AU - A G Tyers TI - X linked dominant congenital isolated bilateral ptosis: the definition and characterisation of a new condition AID - 10.1136/bjo.85.1.70 DP - 2001 Jan 01 TA - British Journal of Ophthalmology PG - 70--73 VI - 85 IP - 1 4099 - http://bjo.bmj.com/content/85/1/70.short 4100 - http://bjo.bmj.com/content/85/1/70.full SO - Br J Ophthalmol2001 Jan 01; 85 AB - AIMS To characterise the inheritance of ptosis in one particular pedigree. METHODS The pedigree was analysed clinically and genetically to assess the mode of inheritance and to ascribe a gene locus for the condition. RESULTS Affected members of the pedigree have bilateral symmetrical congenital isolated ptosis, a condition which is linked to genetic markers on the X chromosome in this family. CONCLUSION A pedigree with dominantly inherited congenital bilateral ptosis is presented. The pedigree exhibits X linked dominant inheritance. A new ophthalmic condition was thereby characterised—namely, X linked dominant congenital isolated bilateral ptosis.