RT Journal Article
SR Electronic
T1 Specificity and sensitivity of glaucoma detection in the Japanese population using scanning laser polarimetry
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 70
OP 74
DO 10.1136/bjo.86.1.70
VO 86
IS 1
A1 Shigeo Funaki
A1 Motohiro Shirakashi
A1 Kiyoshi Yaoeda
A1 Haruki Abe
A1 Shiho Kunimatsu
A1 Yasuyuki Suzuki
A1 Goji Tomita
A1 Makoto Araie
A1 Noriko Yamada
A1 Hideya Uchida
A1 Tetsuya Yamamoto
A1 Yoshiaki Kitazawa
YR 2002
UL http://bjo.bmj.com/content/86/1/70.abstract
AB Aims: To investigate the usefulness of the scanning laser polarimeter (GDx; GDx Nerve Fiber Analyzer) for glaucoma detection in the Japanese population, and to investigate the difference in the thickness of retinal nerve fibre layer (RNFL) between normal tension glaucoma (NTG) and primary open angle glaucoma (POAG). Methods: 69 eyes of 69 normal subjects and 115 eyes of 115 chronic open angle glaucoma patients (60 NTG and 55 POAG patients) were studied. The thickness of RNFL was measured with GDx. An eye was diagnosed as glaucomatous, if at least one original GDx variable showed p <5%. The difference in thickness of RNFL between the NTG and POAG groups was then investigated. Results: 46 normal eyes (66.7%) were diagnosed as not glaucomatous (no variables showing p <5%), and 93 glaucomatous eyes (46 NTG and 47 POAG eyes) (80.9%) were diagnosed as glaucomatous. Actual values of average thickness, ellipse average, superior average, and superior integral were significantly lower in the POAG group than those in the NTG group. Conclusions: New variables which elucidate focal RNFL defects or early changes are needed to improve the moderate detection ability found in this present study. The pattern of the change in RNFL may differ in NTG and POAG groups.