PT  - JOURNAL ARTICLE
AU  - Hiti, K
AU  - Walochnik, J
AU  - Haller-Schober, E M
AU  - Faschinger, C
AU  - Aspöck, H
TI  - Viability of <em>Acanthamoeba</em> after exposure to a multipurpose disinfecting contact lens solution and two hydrogen peroxide systems
AID  - 10.1136/bjo.86.2.144
DP  - 2002 Feb 01
TA  - British Journal of Ophthalmology
PG  - 144--146
VI  - 86
IP  - 2
4099  - http://bjo.bmj.com/content/86/2/144.short
4100  - http://bjo.bmj.com/content/86/2/144.full
SO  - Br J Ophthalmol2002 Feb 01; 86
AB  - Background/aim: Contact lens cases contaminated with Acanthamoeba are a major risk factor for an infection of the eye. In this study the anti-Acanthamoeba activity of three different contact lens storage solutions was tested. Methods: A new multipurpose contact lens storage solution (Meni Care Plus) and a two step (Titmus H2O2) and one step (Oxysept Comfort) hydrogen peroxide system were tested for their effects on trophozoites and cysts of three different Acanthamoeba species: A castellanii, A hatchetti, and A lenticulata. Results: After a soaking time of 8 hours (overnight soaking of contact lenses) the Titmus H2O2 0.6% solution showed very good amoebicidal effects, while Oxysept Comfort 3% H2O2 could not effectively destroy the cysts of any of the three tested species. Viable cysts of the species A lenticulata and A hatchetti were still present after exposure to Meni Care Plus (0.0005% PHMB) for 8 hours. Conclusion: Not all of the three tested contact lens storage solutions have sufficient amoebicidal effects. The two step peroxide system Titmus H2O2 is a very effective disinfectant contact lens solution in order to avoid a possible Acanthamoeba infection of the eye.