RT Journal Article
SR Electronic
T1 Viability of <em>Acanthamoeba</em> after exposure to a multipurpose disinfecting contact lens solution and two hydrogen peroxide systems
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 144
OP 146
DO 10.1136/bjo.86.2.144
VO 86
IS 2
A1 Hiti, K
A1 Walochnik, J
A1 Haller-Schober, E M
A1 Faschinger, C
A1 Aspöck, H
YR 2002
UL http://bjo.bmj.com/content/86/2/144.abstract
AB Background/aim: Contact lens cases contaminated with Acanthamoeba are a major risk factor for an infection of the eye. In this study the anti-Acanthamoeba activity of three different contact lens storage solutions was tested. Methods: A new multipurpose contact lens storage solution (Meni Care Plus) and a two step (Titmus H2O2) and one step (Oxysept Comfort) hydrogen peroxide system were tested for their effects on trophozoites and cysts of three different Acanthamoeba species: A castellanii, A hatchetti, and A lenticulata. Results: After a soaking time of 8 hours (overnight soaking of contact lenses) the Titmus H2O2 0.6% solution showed very good amoebicidal effects, while Oxysept Comfort 3% H2O2 could not effectively destroy the cysts of any of the three tested species. Viable cysts of the species A lenticulata and A hatchetti were still present after exposure to Meni Care Plus (0.0005% PHMB) for 8 hours. Conclusion: Not all of the three tested contact lens storage solutions have sufficient amoebicidal effects. The two step peroxide system Titmus H2O2 is a very effective disinfectant contact lens solution in order to avoid a possible Acanthamoeba infection of the eye.