PT - JOURNAL ARTICLE AU - F Mori AU - S Konno AU - T Hikichi AU - Y Yamaguchi AU - S Ishiko AU - A Yoshida TI - Factors affecting pulsatile ocular blood flow in normal subjects AID - 10.1136/bjo.85.5.529 DP - 2001 May 01 TA - British Journal of Ophthalmology PG - 529--530 VI - 85 IP - 5 4099 - http://bjo.bmj.com/content/85/5/529.short 4100 - http://bjo.bmj.com/content/85/5/529.full SO - Br J Ophthalmol2001 May 01; 85 AB - BACKGROUND The factors that influence pulsatile ocular blood flow (POBF) were evaluated in normal subjects. METHODS POBF was measured in 80 normal subjects using Langham OBF computerised tonometry. The effect of age, systolic and diastolic blood pressure, refractive error, intraocular pressure, and axial length on POBF was evaluated using multiple regression analysis. RESULTS The mean (SD) POBF value was 593.3 (203.6) μl/min (range 290.7–1201.6). Of all the independent variables in the model, only the axial length was statistically significant (p=0.008). The regression coefficient was negative, indicating that the axial length decreased with increasing POBF. CONCLUSIONS These data suggest that, in normal subjects, the POBF decreases as axial length increases. Choroidal blood flow may decrease as the axial length increases. The axial length may therefore be a major factor affecting POBF.