RT Journal Article
SR Electronic
T1 Factors affecting pulsatile ocular blood flow in normal subjects
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 529
OP 530
DO 10.1136/bjo.85.5.529
VO 85
IS 5
A1 F Mori
A1 S Konno
A1 T Hikichi
A1 Y Yamaguchi
A1 S Ishiko
A1 A Yoshida
YR 2001
UL http://bjo.bmj.com/content/85/5/529.abstract
AB BACKGROUND The factors that influence pulsatile ocular blood flow (POBF) were evaluated in normal subjects. METHODS POBF was measured in 80 normal subjects using Langham OBF computerised tonometry. The effect of age, systolic and diastolic blood pressure, refractive error, intraocular pressure, and axial length on POBF was evaluated using multiple regression analysis. RESULTS The mean (SD) POBF value was 593.3 (203.6) μl/min (range 290.7–1201.6). Of all the independent variables in the model, only the axial length was statistically significant (p=0.008). The regression coefficient was negative, indicating that the axial length decreased with increasing POBF. CONCLUSIONS These data suggest that, in normal subjects, the POBF decreases as axial length increases. Choroidal blood flow may decrease as the axial length increases. The axial length may therefore be a major factor affecting POBF.