RT Journal Article
SR Electronic
T1 Intraocular pressure associations with refractive error and axial length in children
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 5
OP 7
DO 10.1136/bjo.88.1.5
VO 88
IS 1
A1 Lee, A J
A1 Saw, S-M
A1 Gazzard, G
A1 Cheng, A
A1 Tan, D T H
YR 2004
UL http://bjo.bmj.com/content/88/1/5.abstract
AB Aim: To assess whether intraocular pressure (IOP) is associated with refractive error or axial length in children. Methods: Of subjects from the Singapore Cohort Study of the Risk Factors for Myopia (SCORM), 636 Chinese children aged 9–11 years from two elementary schools underwent non-contact tonometry, cycloplegic autorefraction, and A-scan biometry during 2001. For analyses, refractive error was categorised into four groups; hypermetropia (spherical equivalent refraction (SE) ⩾+1.0D), emmetropia (−0.5D<SE<+1.0D), low myopia (−3.0D<SE⩽−0.5D) and high myopia (SE⩽−3.0D). Results: Of the 636 children examined, 50.6% were male. The mean IOP was 16.6 (SD 2.7) mm Hg. There were no significant IOP differences between low (mean IOP = 16.4 (2.8) mm Hg) or high myopes (16.7 (2.5) mm Hg) and emmetropes (16.7 (2.9) mm Hg), p = 0.57. IOP was not correlated with spherical equivalent refraction (Spearman correlation, r = 0.009) or axial length (r = 0.030). In regression analyses adjusting for diastolic blood pressure, neither spherical equivalent (regression coefficient = 0.014) nor axial length (regression coefficient = 0.027) were significantly associated with IOP. Conclusion: These findings do not support an association between IOP and refractive error or axial length in children. This questions postulated roles of IOP in the pathogenesis of myopia.