PT  - JOURNAL ARTICLE
AU  - C Chen
AU  - D Louis
AU  - T Dodd
AU  - J Muecke
TI  - Mitomycin C as an adjunct in the treatment of localised ocular surface squamous neoplasia
AID  - 10.1136/bjo.88.1.17
DP  - 2004 Jan 01
TA  - British Journal of Ophthalmology
PG  - 17--18
VI  - 88
IP  - 1
4099  - http://bjo.bmj.com/content/88/1/17.short
4100  - http://bjo.bmj.com/content/88/1/17.full
SO  - Br J Ophthalmol2004 Jan 01; 88
AB  - Aim: To report the outcome of topical mitomycin C (MMC) used as adjunctive treatment following primary excision of ocular surface squamous neoplasia (OSSN). Method: Prospective, non-comparative interventional case series of 27 primary OSSN lesions from 26 patients treated in a single ocular oncology centre over a 4 year period. Result: 27 cases of OSSN received a treatment regimen of surgical excision, followed by topical MMC. Mean follow up of 27 (SD 12) months (range 12–50, median 25 months) revealed zero recurrences. Conclusion: MMC treatment following surgical excision decreases the recurrence rate of primary ocular surface neoplasia and should be considered as adjunctive therapy in primary treatment.