PT  - JOURNAL ARTICLE
AU  - A Y Firth
AU  - S Pulling
AU  - M P Carr
AU  - A Y Beaini
TI  - Orthoptic status before and immediately after heroin detoxification
AID  - 10.1136/bjo.2003.032334
DP  - 2004 Sep 01
TA  - British Journal of Ophthalmology
PG  - 1186--1190
VI  - 88
IP  - 9
4099  - http://bjo.bmj.com/content/88/9/1186.short
4100  - http://bjo.bmj.com/content/88/9/1186.full
SO  - Br J Ophthalmol2004 Sep 01; 88
AB  - Aim: To determine whether changes in orthoptic status take place during withdrawal from heroin and/or methadone. Method: A prospective study of patients, using a repeated measures design, attending a 5 day naltrexone compressed opiate detoxification programme. Results: 83 patients were seen before detoxification (mean age 27.1 (SD 4.6) years) and 69 after detoxification. The horizontal angle of deviation became less exo/more eso at distance (p<0.001) but no significant change was found at near (p = 0.069). Stereoacuity, visual acuity, and convergence were found to be reduced in the immediate post-detoxification period. Prism fusion range, refractive error, subjective accommodation, and objective accommodation at 33 cm did not reduce but a small decrease was found in objective accommodation at 20 cm. Conclusions: The eso trend found in these patients may be responsible for the development of acute concomitant esotropia in some patients undergoing heroin detoxification. However, the mechanism for this trend does not appear to be caused by divergence insufficiency or sixth nerve palsy.