TY - JOUR T1 - A pilot study on the use of a perfluorohexyloctane/silicone oil solution as a heavier than water internal tamponade agent JF - British Journal of Ophthalmology JO - Br J Ophthalmol SP - 662 LP - 665 DO - 10.1136/bjo.2004.055178 VL - 89 IS - 6 AU - D Wong AU - J C Van Meurs AU - T Stappler AU - C Groenewald AU - I A Pearce AU - J N McGalliard AU - E Manousakis AU - E N Herbert Y1 - 2005/06/01 UR - http://bjo.bmj.com/content/89/6/662.abstract N2 - Aims: To report a prospective two centred non-comparative interventional pilot study of a solution of perfluorohexyloctane and silicone oil (Densiron-68) as a heavier than water internal tamponade. Methods: 42 consecutive patients were recruited. The indications include proliferative vitreoretinopathy, retinal detachments arising from inferior retinal breaks, and inability to posture. Results: The success rate with one operation using Densiron was 81% and with further surgery 93%. At the end of the study all tamponade agents were removed in 90% of patients. Visual acuity improved from mean logMAR of 1.41 (SD 0.64) to 0.94 (SD 0.57), pā€Š=ā€Š0.001. There was little evidence of dispersion and excessive inflammation. Conclusion: This new tamponade agent is being compared to conventional silicone oil in a prospective international randomised trial. ER -