TY - JOUR T1 - Prevalence and spectrum of bacterial co-infection during fungal keratitis JF - British Journal of Ophthalmology JO - Br J Ophthalmol SP - 289 LP - 292 DO - 10.1136/bjo.2005.081869 VL - 90 IS - 3 AU - J C Pate AU - D B Jones AU - K R Wilhelmus Y1 - 2006/03/01 UR - http://bjo.bmj.com/content/90/3/289.abstract N2 - Aims: To estimate the propensity of keratomycosis for parallel or secondary bacterial infection and to explore affinities among fungal and bacterial co-isolates. Methods: A retrospective review of laboratory records over 24 years yielded 152 episodes of culture positive fungal keratitis. After collating 65 corneal specimens having bacterial co-isolates, polymicrobial co-infection was defined as detection of concordant bacteria on smear and culture or on two or more different media. Results: 30 (20%) keratomycoses met laboratory criteria for polymicrobial infection. The risk of bacterial co-infection was 3.2 (95% confidence interval, 1.7 to 5.8) times greater with yeast keratitis than with filamentous fungal keratitis. Conclusions: Bacterial co-infection occasionally complicates fungal keratitis, particularly candidiasis. ER -