PT  - JOURNAL ARTICLE
AU  - Jian Li
AU  - Gerald McGwin, Jr
AU  - Michael S Vaphiades
AU  - Cynthia Owsley
TI  - Non-arteritic anterior ischaemic optic neuropathy and presumed sleep apnoea syndrome screened by the Sleep Apnea scale of the Sleep Disorders Questionnaire (SA-SDQ)
AID  - 10.1136/bjo.2006.113803
DP  - 2007 Nov 01
TA  - British Journal of Ophthalmology
PG  - 1524--1527
VI  - 91
IP  - 11
4099  - http://bjo.bmj.com/content/91/11/1524.short
4100  - http://bjo.bmj.com/content/91/11/1524.full
SO  - Br J Ophthalmol2007 Nov 01; 91
AB  - Background: Two recent studies reported over 70% of the patients with non-arteritic anterior ischaemic optic neuropathy (NAION) had sleep apnoea syndrome (SAS) diagnosed by overnight polysomnography. The current study used the Sleep Apnea scale of the Sleep Disorders Questionnaire (SA-SDQ) to evaluate this association.Methods: A matched case-control study was conducted among 73 cases of NAION matched on age and gender to 73 controls without a history of NAION. Information regarding demographics, medical conditions, health behaviours and SAS was obtained via a telephone questionnaire that included the SA-SDQ. Conditional logistic regression was used to calculate odds ratios (OR) and the 95% confidence intervals (CI) for the association between NAION and the SA-SDQ.Results: Cases were significantly more likely to report symptoms and characteristics consistent with SAS than controls (OR 2.62; 95% CI 1.03 to 6.60) when adjusted for medical and health behaviour characteristics.Conclusions: The results of this study suggest that patients with SAS are at increased risk of NAION. Additional research in a larger population is needed to confirm the observed results and validate the use of the SA-SDQ in patients with NAION.