PT  - JOURNAL ARTICLE
AU  - N Sagara
AU  - T Kawaji
AU  - Y Koshiyama
AU  - Y Inomata
AU  - M Fukushima
AU  - H Tanihara
TI  - Macular hole formation after macular haemorrhage associated with rupture of retinal arterial macroaneurysm
AID  - 10.1136/bjo.2008.149195
DP  - 2009 Oct 01
TA  - British Journal of Ophthalmology
PG  - 1337--1340
VI  - 93
IP  - 10
4099  - http://bjo.bmj.com/content/93/10/1337.short
4100  - http://bjo.bmj.com/content/93/10/1337.full
SO  - Br J Ophthalmol2009 Oct 01; 93
AB  - Aim: To investigate the frequency and risk factors of macular hole (MH) formation after rupture of a retinal arterial macroaneurysm.Methods: Fifty-six eyes from 56 patients with rupture of a retinal arterial macroaneurysm with or without an MH (MH and non-MH groups, respectively) were reviewed. Frequency and risk factors related to MH formation were assessed, with risk factors including age; sex; distance from the macroaneurysm to the fovea; incidence of haemorrhages involving the macula such as preretinal, subinternal limiting membrane (sub-ILM), subretinal and vitreous; and vitreous surgery. MH formation in these patients was recorded and analysed.Results: Of the 56 eyes reviewed, seven (12.5%) had an MH after rupture of the retinal arterial macroaneurysm. The incidence of subretinal and sub-ILM haemorrhages involving the macula was significantly greater in the MH group than in the non-MH group (p = 0.037 and 0.045, respectively).Conclusion: These results suggest that the presence of subretinal and sub-ILM haemorrhages after rupture of a retinal arterial macroaneurysm may contribute to formation of an MH.