TY - JOUR T1 - Toxic corneal oedema associated with amantadine use JF - British Journal of Ophthalmology JO - Br J Ophthalmol SP - 281 LP - 281 DO - 10.1136/bjo.2007.135731 VL - 93 IS - 3 AU - A Pond AU - M S Lee AU - D R Hardten AU - A R Harrison AU - J H Krachmer Y1 - 2009/03/01 UR - http://bjo.bmj.com/content/93/3/281.abstract N2 - Amantadine HCl is an antiviral agent used to treat and prevent influenza A. It is also indicated for the treatment of Parkinsonism and drug-induced extrapyramidal symptoms.[1] Off-label uses include multiple sclerosis, Alzheimer disease and attention-deficit/hyperactivity disorder (ADHD). We report two patients with reversible, profound visual loss and corneal oedema associated with amantadine use.Case 1A 12-year-old girl with generalised anxiety … ER -