TY - JOUR T1 - ANSWERS JF - British Journal of Ophthalmology JO - Br J Ophthalmol SP - 413 LP - 413 DO - 10.1136/bjo.2007.135731a VL - 93 IS - 3 A2 - , Y1 - 2009/03/01 UR - http://bjo.bmj.com/content/93/3/413.abstract N2 - From questions on page 281These patients did not have a family history of Fuchs corneal dystrophy or a history of trauma or surgery. There was no evidence of inflammation or corneal guttata. A review of their medications revealed the use of amantadine, which has reportedly caused corneal oedema.Before the cause of oedema was recognised, case 1 had been scheduled for corneal transplantation. In both cases, the only intervention was to stop amantadine. In case 1, the patient described normalisation of her vision within 10 days of discontinuation of amantadine. At 1 month’s follow-up, her best corrected visual acuities were 20/20, right eye and 20/25, left eye. By slit-lamp … ER -