PT  - JOURNAL ARTICLE
AU  - D H Tran
AU  - C Souza
AU  - M J Ang
AU  - J Loman
AU  - S K Law
AU  - A L Coleman
AU  - J Caprioli
TI  - Comparison of long-term surgical success of Ahmed Valve implant versus trabeculectomy in open-angle glaucoma
AID  - 10.1136/bjo.2008.150870
DP  - 2009 Nov 01
TA  - British Journal of Ophthalmology
PG  - 1504--1509
VI  - 93
IP  - 11
4099  - http://bjo.bmj.com/content/93/11/1504.short
4100  - http://bjo.bmj.com/content/93/11/1504.full
SO  - Br J Ophthalmol2009 Nov 01; 93
AB  - Aim: To compare the long-term intraocular pressure (IOP) outcomes of Ahmed Glaucoma Valve (AGV) implantation to trabeculectomy with mitomycin C (MMC) in open-angle glaucoma (OAG).Methods: 78 OAG patients who underwent AGV implantation were matched with respect to age, preoperative surgery, preoperative IOP and preoperative medicines to 88 OAG patients who underwent trabeculectomy with MMC with a minimum of 3 years’ follow-up. The cumulative probability of success between the two groups with different criteria was analysed: (1) an IOP⩽21 mm Hg and a reduction of IOP⩾15% from baseline; and (2) an IOP⩽18 mm Hg and a reduction of IOP⩾20% from baseline. No loss of light perception, no additional glaucoma surgery and no hypotony were also required.Results: The 5-year cumulative probability of success was not statistically significant between eyes that had an AGV or trabeculectomy with MMC when success was defined as criteria A (p = 0.094). However, when success was defined according to criteria B, eyes undergoing trabeculectomy with MMC had a higher rate of success (p = 0.024).Conclusions: Trabeculectomy with MMC has a significantly higher 5-year cumulative probability of success compared with AGV implants when greater reduction IOP is necessary.