RT Journal Article SR Electronic T1 Unexplained vision loss following removal of epiretinal membrane JF British Journal of Ophthalmology JO Br J Ophthalmol FD BMJ Publishing Group Ltd. SP 1033 OP 1039 DO 10.1136/bjo.2009.173757 VO 94 IS 8 A1 R H Roe A1 H R McDonald A1 A D Fu A1 J M Lahey A1 R T Wendel A1 J A Pearlman A1 P M Monahan A1 J M Jumper A1 R N Johnson A1 E Ai A1 E T Cunningham YR 2010 UL http://bjo.bmj.com/content/94/8/1033.abstract AB Purpose To report unexplained severe central vision loss accompanied by a dense central scotoma as an uncommon complication following epiretinal membrane removal.Methods Retrospective, multicentred, case series.Results Six patients underwent uncomplicated vitrectomy surgery between 2000 and 2007 at four separate retina practices for removal of an epiretinal membrane. Preoperative vision ranged from 20/60 to 20/100, with a median of 20/70. On the first day postoperatively, all patients noted decreased vision ranging from counting fingers to light perception and were found to have a dense central scotoma. Posterior segment examination revealed a white, oedematous macula in all affected eyes. Vision improved minimally during the follow-up period, which ranged from 2 months to 5 years. The final vision ranged from 20/200 to hand movements. No anatomic or physiologic cause for the decreased vision and central scotoma was identified.Conclusions While uncommon, severe, permanent, central vision loss accompanied by a dense central scotoma can occur following epiretinal membrane removal and should be considered when assessing the risks and benefits of such surgery.