RT Journal Article SR Electronic T1 Trends in corneal graft surgery in the UK JF British Journal of Ophthalmology JO Br J Ophthalmol FD BMJ Publishing Group Ltd. SP 468 OP 472 DO 10.1136/bjo.2010.182329 VO 95 IS 4 A1 Tiarnan D L Keenan A1 Fiona Carley A1 David Yeates A1 Mark N A Jones A1 Sally Rushton A1 Michael J Goldacre YR 2011 UL http://bjo.bmj.com/content/95/4/468.abstract AB Aims The aims of this study were to examine trends over time and regional variation in rates of corneal graft surgery in the UK.Methods The hospital in-patient enquiry (HIPE) and hospital episode statistics (HES) were analysed for keratoplasty admissions in England from 1971 to 2006. NHS Blood and Transplant (NHSBT) data were analysed for keratoplasty operations in the UK from 1999 to 2009.Results Annual rates of penetrating keratoplasty (PK) under HIPE and HES increased from 0.7 per 100 000 population (1971) to 3.9 (1992), then decreased to 3.1 (2006). Rates of lamellar keratoplasty (LK) increased from 0.1 (1971) to 0.9 (2006). Annual PK operations under NHSBT decreased from 1901 (1999/00) to 1473 (2008/9). Over the same period, deep anterior lamellar keratoplasty operations increased from 91 to 327 per year, while endothelial keratoplasty operations increased from 2 to 569 per year. Geographical analysis showed a wide variation across local authority areas in rates of keratoplasty around 1998–2004, especially for LK.Conclusion The total number of corneal graft operations performed in the UK has increased slowly over the past decade. The proportion of lamellar versus penetrating keratoplasty has increased, with LK performed at the highest rates in specialist centres distributed across the UK.