PT  - JOURNAL ARTICLE
AU  - Wilson Low
AU  - Mohamed Dirani
AU  - Gus Gazzard
AU  - Yiong-Huak Chan
AU  - Hui-Jun Zhou
AU  - Prabakaran Selvaraj
AU  - Kah-Guan Au Eong
AU  - Terri L Young
AU  - Paul Mitchell
AU  - Tien-Yin Wong
AU  - Seang-Mei Saw
TI  - Family history, near work, outdoor activity, and myopia in Singapore Chinese preschool children
AID  - 10.1136/bjo.2009.173187
DP  - 2010 Aug 01
TA  - British Journal of Ophthalmology
PG  - 1012--1016
VI  - 94
IP  - 8
4099  - http://bjo.bmj.com/content/94/8/1012.short
4100  - http://bjo.bmj.com/content/94/8/1012.full
SO  - Br J Ophthalmol2010 Aug 01; 94
AB  - Aims To investigate the risk factors for myopia, including near work and outdoor activity, in Singapore Chinese preschool children.Methods A cross-sectional study, with disproportionate random sampling by 6-month age groups, of 3009 Singapore Chinese children aged 6–72 months was performed. Information on family history, near work and outdoor activity was obtained. Spherical equivalent refraction (SER) was assessed.Results Children with two myopic parents were more likely to be myopic (adjusted OR=1.91; 95% CI 1.38 to 2.63) and to have a more myopic SER (regression coefficient=−0.35; 95% CI −0.47 to −0.22) than children without myopic parents. For each 1 cm taller height, the SER was more myopic by 0.01 dioptres. Neither near work nor outdoor activity was associated with preschool myopia.Conclusions A family history of myopia was the strongest factor associated with preschool myopia. In contrast, neither near work nor outdoor activity was found to be associated with early myopia. These data suggest that genetic factors may play a more substantial role in the development of early-onset myopia than key environmental factors.