PT  - JOURNAL ARTICLE
AU  - Marie-Claude Robert
AU  - Krystel Moussally
AU  - Mona Harissi-Dagher
TI  - Review of endophthalmitis following Boston keratoprosthesis type 1
AID  - 10.1136/bjophthalmol-2011-301263
DP  - 2012 Jun 01
TA  - British Journal of Ophthalmology
PG  - 776--780
VI  - 96
IP  - 6
4099  - http://bjo.bmj.com/content/96/6/776.short
4100  - http://bjo.bmj.com/content/96/6/776.full
SO  - Br J Ophthalmol2012 Jun 01; 96
AB  - Endophthalmitis remains one of the most damaging and challenging complications following Boston keratoprosthesis type 1 (KPro) surgery. The authors reviewed the literature from 2001 onward to identify cases of endophthalmitis following KPro surgery and present an additional case of endophthalmitis in a patient with Stevens Johnson syndrome. The prevalence of endophthalmitis between 2001 and 2011 was 5.4%. Gram-positive bacteria are the most common agents responsible for endophthalmitis in this patient population while gram-negative bacteria and fungi are emerging pathogens. Risk factors for endophthalmitis include preoperative diagnosis of cicatricial disease and postoperative infectious keratitis, glaucoma drainage device erosion and non-compliance with antibiotic prophylaxis. Additional studies on the prevention and treatment of endophthalmitis are required to improve the overall prognosis of these patients.