RT Journal Article
SR Electronic
T1 Review of endophthalmitis following Boston keratoprosthesis type 1
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 776
OP 780
DO 10.1136/bjophthalmol-2011-301263
VO 96
IS 6
A1 Marie-Claude Robert
A1 Krystel Moussally
A1 Mona Harissi-Dagher
YR 2012
UL http://bjo.bmj.com/content/96/6/776.abstract
AB Endophthalmitis remains one of the most damaging and challenging complications following Boston keratoprosthesis type 1 (KPro) surgery. The authors reviewed the literature from 2001 onward to identify cases of endophthalmitis following KPro surgery and present an additional case of endophthalmitis in a patient with Stevens Johnson syndrome. The prevalence of endophthalmitis between 2001 and 2011 was 5.4%. Gram-positive bacteria are the most common agents responsible for endophthalmitis in this patient population while gram-negative bacteria and fungi are emerging pathogens. Risk factors for endophthalmitis include preoperative diagnosis of cicatricial disease and postoperative infectious keratitis, glaucoma drainage device erosion and non-compliance with antibiotic prophylaxis. Additional studies on the prevention and treatment of endophthalmitis are required to improve the overall prognosis of these patients.